Tumor-infiltrating lymphocytes and outcome in Merkel cell carcinoma, a virus-associated cancer
H Sihto, H Joensuu - Oncoimmunology, 2012 - Taylor & Francis
H Sihto, H Joensuu
Oncoimmunology, 2012•Taylor & FrancisAn intense immune infiltrate, enriched in T cells, is associated with the presence of Merkel
cell polyomavirus (MCPyV) DNA in Merkel cell carcinoma (MCC), a rare skin cancer. High
tumor-infiltrating T-cell counts are associated with favorable survival regardless of the tumor
MCPyV status. Hence, boosting host immune functions might constitute a new approach for
the treatment of MCC.
cell polyomavirus (MCPyV) DNA in Merkel cell carcinoma (MCC), a rare skin cancer. High
tumor-infiltrating T-cell counts are associated with favorable survival regardless of the tumor
MCPyV status. Hence, boosting host immune functions might constitute a new approach for
the treatment of MCC.
An intense immune infiltrate, enriched in T cells, is associated with the presence of Merkel cell polyomavirus (MCPyV) DNA in Merkel cell carcinoma (MCC), a rare skin cancer. High tumor-infiltrating T-cell counts are associated with favorable survival regardless of the tumor MCPyV status. Hence, boosting host immune functions might constitute a new approach for the treatment of MCC.
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