COPII and COPI traffic at the ER-Golgi interface
T Szul, E Sztul - Physiology, 2011 - journals.physiology.org
T Szul, E Sztul
Physiology, 2011•journals.physiology.orgProtein traffic is necessary to maintain homeostasis in all eukaryotic organisms. All newly
synthesized secretory proteins destined to the secretory and endolysosmal systems are
transported from the endoplasmic reticulum to the Golgi before delivery to their final
destinations. Here, we describe the COPII and COPI coating machineries that generate
carrier vesicles and the tethers and SNAREs that mediate COPII and COPI vesicle fusion at
the ER-Golgi interface.
synthesized secretory proteins destined to the secretory and endolysosmal systems are
transported from the endoplasmic reticulum to the Golgi before delivery to their final
destinations. Here, we describe the COPII and COPI coating machineries that generate
carrier vesicles and the tethers and SNAREs that mediate COPII and COPI vesicle fusion at
the ER-Golgi interface.
Protein traffic is necessary to maintain homeostasis in all eukaryotic organisms. All newly synthesized secretory proteins destined to the secretory and endolysosmal systems are transported from the endoplasmic reticulum to the Golgi before delivery to their final destinations. Here, we describe the COPII and COPI coating machineries that generate carrier vesicles and the tethers and SNAREs that mediate COPII and COPI vesicle fusion at the ER-Golgi interface.
American Physiological Society