Diagnosis and treatment of alcohol-associated liver disease: a review
AK Singal, P Mathurin - Jama, 2021 - jamanetwork.com
Importance Alcohol-associated liver disease results in cirrhosis in approximately 10% to
20% of patients. In 2017, more than 2 million people had alcohol-associated cirrhosis in the
US. Alcohol-associated liver disease is the primary cause of liver-related mortality and the
leading indication for liver transplant, representing 40% to 50% of all liver transplant in high-
income countries. Observations Steatosis, alcoholic hepatitis, and fibrosis are the 3
pathologic findings that are associated with progression to cirrhosis, with highest risk in …
20% of patients. In 2017, more than 2 million people had alcohol-associated cirrhosis in the
US. Alcohol-associated liver disease is the primary cause of liver-related mortality and the
leading indication for liver transplant, representing 40% to 50% of all liver transplant in high-
income countries. Observations Steatosis, alcoholic hepatitis, and fibrosis are the 3
pathologic findings that are associated with progression to cirrhosis, with highest risk in …