No prospective study has analyzed simultaneously chronic viral hepatitis and alcoholism as
risk factors for liver carcinogenesis, while taking into consideration the role of cirrhosis. Nor
has the risk for hepatocellular carcinoma among patients with chronic viral hepatitis been
prospectively evaluated in a low-risk Western population. Last, the relationship between
hepatocellular carcinoma risk factors and bile duct cancer remains to be clarified. We
analyzed prospectively the risk for primary liver and extrahepatic biliary tract cancer among …