Large-scale gene profiling of the liver in a mouse model of chronic, intragastric ethanol infusion
IV Deaciuc, DE Doherty, R Burikhanov, EY Lee… - Journal of …, 2004 - Elsevier
Background/Aims: The mechanisms underlying alcohol-induced liver injury are not fully
elucidated. An approach in this direction would consist of an all-inclusive assessment of
gene expression in the liver. The purpose of this study was to perform a comprehensive
analysis of gene expression in the livers of mice treated with ethanol by means of
intragastric infusion. Methods: An ethanol-or glucose-enriched liquid diet was fed to animals
for 4 weeks via a long-term gastrostomy catheter. The animals were killed and plasma …
elucidated. An approach in this direction would consist of an all-inclusive assessment of
gene expression in the liver. The purpose of this study was to perform a comprehensive
analysis of gene expression in the livers of mice treated with ethanol by means of
intragastric infusion. Methods: An ethanol-or glucose-enriched liquid diet was fed to animals
for 4 weeks via a long-term gastrostomy catheter. The animals were killed and plasma …