Landmark trials in the medical oncology management of metastatic breast cancer
P Lu, CA Santa-Maria, TJ Ballinger, JY Sheng - Seminars in oncology, 2021 - Elsevier
Significant advances in the management of metastatic breast cancer (MBC) have guided
more personalized treatment according to disease biology and led to improved survival
outcomes and quality of life for patients. In this review, we discuss landmark clinical trials in
medical oncology that have shaped the current standard of care for MBC. Combinations of
endocrine therapy with cyclin-dependent kinase 4/6 inhibitors have led to substantial
improvements in overall survival, thus becoming standard first-line treatment for patients with …
more personalized treatment according to disease biology and led to improved survival
outcomes and quality of life for patients. In this review, we discuss landmark clinical trials in
medical oncology that have shaped the current standard of care for MBC. Combinations of
endocrine therapy with cyclin-dependent kinase 4/6 inhibitors have led to substantial
improvements in overall survival, thus becoming standard first-line treatment for patients with …