[HTML][HTML] Role of α1 and α2 chains of type IV collagen in early fibrotic lesions of idiopathic interstitial pneumonias and migration of lung fibroblasts
H Urushiyama, Y Terasaki, S Nagasaka… - Laboratory …, 2015 - Elsevier
Early fibrotic lesions are thought to be the initial findings of fibrogenesis in idiopathic
interstitial pneumonias, but little is known about their properties. Type IV collagen comprises
six gene products, α1–α6, and although it is known as a major basement membrane
component, its abnormal deposition is seen in fibrotic lesions of certain organs. We studied
the expression of type I and III collagen and all α chains of type IV collagen in lung
specimens from patients with usual interstitial pneumonia (UIP) or organizing pneumonia …
interstitial pneumonias, but little is known about their properties. Type IV collagen comprises
six gene products, α1–α6, and although it is known as a major basement membrane
component, its abnormal deposition is seen in fibrotic lesions of certain organs. We studied
the expression of type I and III collagen and all α chains of type IV collagen in lung
specimens from patients with usual interstitial pneumonia (UIP) or organizing pneumonia …