[HTML][HTML] Elongation factor-1α is a novel protein associated with host cell invasion and a potential protective antigen of Cryptosporidium parvum

M Matsubayashi, I Teramoto-Kimata, S Uni… - Journal of Biological …, 2013 - ASBMB
The phylum Apicomplexa comprises obligate intracellular parasites that infect vertebrates.
All invasive forms of Apicomplexa possess an apical complex, a unique assembly of
organelles localized to the anterior end of the cell and involved in host cell invasion.
Previously, we generated a chicken monoclonal antibody (mAb), 6D-12-G10, with specificity
for an antigen located in the apical cytoskeleton of Eimeria acervulina sporozoites. This
antigen was highly conserved among Apicomplexan parasites, including other Eimeria spp …