A new modular protein of Cryptosporidium parvum, with ricin B and LCCL domains, expressed in the sporozoite invasive stage
F Tosini, A Agnoli, R Mele, MAG Morales… - Molecular and …, 2004 - Elsevier
The recombinant SA35 peptide has been described as an antigenic portion of a larger
Cryptosporidium parvum protein. We identified and characterized the encoding Cpa135
gene and the entire protein, Cpa135. The Cpa135 gene was found to consist of a single
exon of 4671bp, and the mRNA transcribed in the sporozoites was identified. The predicted
1556 amino-acid protein showed the presence of domains which are widely conserved also
in other unrelated phylogenetic groups (ie a ricin B and a LCCL motif). Comparison of …
Cryptosporidium parvum protein. We identified and characterized the encoding Cpa135
gene and the entire protein, Cpa135. The Cpa135 gene was found to consist of a single
exon of 4671bp, and the mRNA transcribed in the sporozoites was identified. The predicted
1556 amino-acid protein showed the presence of domains which are widely conserved also
in other unrelated phylogenetic groups (ie a ricin B and a LCCL motif). Comparison of …