Comparison of pp65 antigenemia, quantitative PCR and DNA hybrid capture for detection of cytomegalovirus in transplant recipients and AIDS patients
L Mhiri, B Kaabi, M Houimel, Z Arrouji, A Slim - Journal of virological …, 2007 - Elsevier
The cytomegalovirus (CMV) antigenemia assay has been used frequently for rapid
diagnosis of CMV infection, and antigenemia threshold values are recommended for
triggering preemptive therapy. Hybrid capture of CMV's DNA and quantitative polymerase
chain reaction (qPCR) are increasingly being adopted for early detection of CMV. The
performance of the antigenemia assay, qPCR in plasma and hybrid capture in leukocytes
were compared in 110 immunocompromised patients (38 bone-marrow transplants, 50 renal …
diagnosis of CMV infection, and antigenemia threshold values are recommended for
triggering preemptive therapy. Hybrid capture of CMV's DNA and quantitative polymerase
chain reaction (qPCR) are increasingly being adopted for early detection of CMV. The
performance of the antigenemia assay, qPCR in plasma and hybrid capture in leukocytes
were compared in 110 immunocompromised patients (38 bone-marrow transplants, 50 renal …