Interleukin-12 (IL-12) and IL-18 are important in innate defense against genital herpes simplex virus type 2 infection in mice but are not required for the development of …
AM Harandi, B Svennerholm, J Holmgren… - Journal of …, 2001 - Am Soc Microbiol
Journal of Virology, 2001•Am Soc Microbiol
Using a combination of gene-targeted mice and neutralizing antibodies, we showed that
interleukin-12 (IL-12) and IL-18 are important in the innate control of genital herpes simplex
virus type 2 infection but were not found to be critical, either singly or in combination, for the
development of a protective gamma interferon-mediated immune response.
interleukin-12 (IL-12) and IL-18 are important in the innate control of genital herpes simplex
virus type 2 infection but were not found to be critical, either singly or in combination, for the
development of a protective gamma interferon-mediated immune response.
Abstract
Using a combination of gene-targeted mice and neutralizing antibodies, we showed that interleukin-12 (IL-12) and IL-18 are important in the innate control of genital herpes simplex virus type 2 infection but were not found to be critical, either singly or in combination, for the development of a protective gamma interferon-mediated immune response.
American Society for Microbiology