[HTML][HTML] The human memory T cell compartment changes across tissues of the female reproductive tract
ASW Davis, SC Vick, L Pattacini, V Voillet… - Mucosal …, 2021 - Elsevier
Memory CD4 T cells in tissues fulfill numerous functions that are critical for local immune
homeostasis and protection against pathogens. Previous studies have highlighted the
phenotypic and functional heterogeneity of circulating and tissue-resident memory CD4 T
cells across different human tissues such as skin, lung, liver, and colon. Comparatively little
is known in regard to memory CD4 T cells across tissues of the female reproductive tract
(FRT). We examined CD4 T cells in donor-matched vaginal, ecto-and endocervical tissues …
homeostasis and protection against pathogens. Previous studies have highlighted the
phenotypic and functional heterogeneity of circulating and tissue-resident memory CD4 T
cells across different human tissues such as skin, lung, liver, and colon. Comparatively little
is known in regard to memory CD4 T cells across tissues of the female reproductive tract
(FRT). We examined CD4 T cells in donor-matched vaginal, ecto-and endocervical tissues …