The role of T-system immunity in reparatory regeneration of the bone tissue in animals.
AA Askalonov, SM Gordienko… - Journal of hygiene …, 1987 - europepmc.org
AA Askalonov, SM Gordienko, OE Avdyunicheva, AV Bondarenko, SF Voronkov
Journal of hygiene, epidemiology, microbiology, and immunology, 1987•europepmc.orgIt has been demonstrated in experiments on mice (CBA X C57BL) X F1, thymectomized and
irradiated by 800 R, with the haemopoietic system restored by bone marrow (B-mice) that in
these animals, as compared with the controls, the changes in cellular immunity (inhibition of
natural killer cells and stimulation of individual functions of the phagocytizing cells) are
accompanied by considerable inhibition of osteogenesis. Compensatory regeneration of
broken thigh-bone in B-mice is delayed by 5--10 days in various elements of the …
irradiated by 800 R, with the haemopoietic system restored by bone marrow (B-mice) that in
these animals, as compared with the controls, the changes in cellular immunity (inhibition of
natural killer cells and stimulation of individual functions of the phagocytizing cells) are
accompanied by considerable inhibition of osteogenesis. Compensatory regeneration of
broken thigh-bone in B-mice is delayed by 5--10 days in various elements of the …
It has been demonstrated in experiments on mice (CBA X C57BL) X F1, thymectomized and irradiated by 800 R, with the haemopoietic system restored by bone marrow (B-mice) that in these animals, as compared with the controls, the changes in cellular immunity (inhibition of natural killer cells and stimulation of individual functions of the phagocytizing cells) are accompanied by considerable inhibition of osteogenesis. Compensatory regeneration of broken thigh-bone in B-mice is delayed by 5--10 days in various elements of the regenerated tissue in comparison with normal mice. Anatomical formation of the provisional callus in B-mice is not completed on day 21 and approaches a 14-day regenerate of the controls. The obtained results suggest the participation of T-system immunity in the reparatory regeneration of bone tissue.
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