[HTML][HTML] Molecular profiling of innate immune response mechanisms in ventilator-associated Pneumonia
KV Pathak, MI McGilvrey, CK Hu… - Molecular & Cellular …, 2020 - ASBMB
Ventilator-associated pneumonia (VAP) is a common hospital-acquired infection, leading to
high morbidity and mortality. Currently, bronchoalveolar lavage (BAL) is used in hospitals for
VAP diagnosis and guiding treatment options. Although BAL collection procedures are
invasive, alternatives such as endotracheal aspirates (ETA) may be of diagnostic value,
however, their use has not been thoroughly explored. Longitudinal ETA and BAL were
collected from 16 intubated patients up to 15 days, of which 11 developed VAP. We …
high morbidity and mortality. Currently, bronchoalveolar lavage (BAL) is used in hospitals for
VAP diagnosis and guiding treatment options. Although BAL collection procedures are
invasive, alternatives such as endotracheal aspirates (ETA) may be of diagnostic value,
however, their use has not been thoroughly explored. Longitudinal ETA and BAL were
collected from 16 intubated patients up to 15 days, of which 11 developed VAP. We …