Discriminating bacterial and viral infection using a rapid host gene expression test
OBJECTIVES: Host gene expression signatures discriminate bacterial and viral infection but
have not been translated to a clinical test platform. This study enrolled an independent
cohort of patients to describe and validate a first-in-class host response bacterial/viral test.
DESIGN: Subjects were recruited from 2006 to 2016. Enrollment blood samples were
collected in an RNA preservative and banked for later testing. The reference standard was
an expert panel clinical adjudication, which was blinded to gene expression and …
have not been translated to a clinical test platform. This study enrolled an independent
cohort of patients to describe and validate a first-in-class host response bacterial/viral test.
DESIGN: Subjects were recruited from 2006 to 2016. Enrollment blood samples were
collected in an RNA preservative and banked for later testing. The reference standard was
an expert panel clinical adjudication, which was blinded to gene expression and …