Association of adverse events with antibiotic use in hospitalized patients

PD Tamma, E Avdic, DX Li, K Dzintars… - JAMA internal …, 2017 - jamanetwork.com
Importance Estimates of the incidence of overall antibiotic-associated adverse drug events
(ADEs) in hospitalized patients are generally unavailable. Objective To describe the
incidence of antibiotic-associated ADEs for adult inpatients receiving systemic antibiotic
therapy. Design, Setting, and Participants Retrospective cohort of adult inpatients admitted
to general medicine wards at an academic medical center. Exposures At least 24 hours of
any parenteral or oral antibiotic therapy. Main Outcomes and Measures Medical records of …