Liver dysfunctions are classified into acute and chronic diseases, which comprise a
heterogeneous group of pathological features and a high mortality rate. Liver transplantation
remains the gold‐standard therapy for most liver diseases, with concomitant limitations
related to donor organ shortage and lifelong immunosuppressive therapy. A concept in liver
therapy intends to overcome these limitations based on the secreted extracellular vesicles
(EVs; microvesicles and exosomes) by mesenchymal stem/stromal cells (MSCs). A …