Pivotal role of glutamine synthetase in ammonia detoxification
TBM Hakvoort, Y He, W Kulik, JLM Vermeulen… - Hepatology, 2017 - journals.lww.com
Materials and Methods Glul fl/fl mice 2 were crossed with Alfp‐Cre 11 and/or Mck‐Cre 10
transgenic mice to eliminate the Glul allele in hepatocytes and striated myocytes,
respectively. These are referred to as GS‐KO/L, GS‐KO/M, and GS‐KO/LM mice.
Hemizygous GS‐deficient (Glul fl/LacZ) mice are referred to as GS‐KO/0.5 mice. For details,
see Supporting Information.
transgenic mice to eliminate the Glul allele in hepatocytes and striated myocytes,
respectively. These are referred to as GS‐KO/L, GS‐KO/M, and GS‐KO/LM mice.
Hemizygous GS‐deficient (Glul fl/LacZ) mice are referred to as GS‐KO/0.5 mice. For details,
see Supporting Information.