Circulating soluble urokinase plasminogen activator receptor levels and peripheral arterial disease outcomes
Background and aims Circulating soluble urokinase plasminogen activator receptor
(suPAR) is a marker of immune activation associated with atherosclerosis. Whether suPAR
levels are associated with prevalent peripheral arterial disease (PAD) and its adverse
outcomes remains unknown and is the aim of the study. Methods SuPAR levels were
measured in 5810 patients (mean age 63 years, 63% male, 77% with obstructive coronary
artery disease [CAD]) undergoing cardiac catheterization. The presence of PAD (n= 967 …
(suPAR) is a marker of immune activation associated with atherosclerosis. Whether suPAR
levels are associated with prevalent peripheral arterial disease (PAD) and its adverse
outcomes remains unknown and is the aim of the study. Methods SuPAR levels were
measured in 5810 patients (mean age 63 years, 63% male, 77% with obstructive coronary
artery disease [CAD]) undergoing cardiac catheterization. The presence of PAD (n= 967 …