Increased expression of T cell activation markers (CD25, CD26, CD40L and CD69) in atherectomy specimens of patients with unstable angina and acute myocardial …
M Hosono, OJ de Boer, AC van der Wal… - Atherosclerosis, 2003 - Elsevier
Atherosclerotic plaques contain a chronic immune mediated inflammation in which T cells
play an important role. A previous study revealed that the numbers of interleukin-2 receptor-
positive T cells is increased in culprit lesions of patients with acute coronary syndromes; a
finding of considerable interest since it indicates a recent change in the intraplaque T cell
mediated immune response. Confirmation of this observation is important, because it could
provide insight into the onset of the acute event. We have, therefore, expanded our earlier …
play an important role. A previous study revealed that the numbers of interleukin-2 receptor-
positive T cells is increased in culprit lesions of patients with acute coronary syndromes; a
finding of considerable interest since it indicates a recent change in the intraplaque T cell
mediated immune response. Confirmation of this observation is important, because it could
provide insight into the onset of the acute event. We have, therefore, expanded our earlier …