[HTML][HTML] Primary dystonia: conceptualizing the disorder through a structural brain imaging lens
RA Ramdhani, K Simonyan - Tremor and other hyperkinetic …, 2013 - ncbi.nlm.nih.gov
RA Ramdhani, K Simonyan
Tremor and other hyperkinetic movements, 2013•ncbi.nlm.nih.govBackground Dystonia is a hyperkinetic movement disorder characterized by involuntary,
repetitive twisting movements. The anatomical structures and pathways implicated in its
pathogenesis and their relationships to the neurophysiological paradigms of abnormal
surround inhibition, maladaptive plasticity, and impaired sensorimotor integration remain
unclear. Objective We review the use of high-resolution structural brain imaging using voxel-
based morphometry (VBM) and diffusion tensor imaging (DTI) techniques for evaluating …
repetitive twisting movements. The anatomical structures and pathways implicated in its
pathogenesis and their relationships to the neurophysiological paradigms of abnormal
surround inhibition, maladaptive plasticity, and impaired sensorimotor integration remain
unclear. Objective We review the use of high-resolution structural brain imaging using voxel-
based morphometry (VBM) and diffusion tensor imaging (DTI) techniques for evaluating …
Abstract
Background
Dystonia is a hyperkinetic movement disorder characterized by involuntary, repetitive twisting movements. The anatomical structures and pathways implicated in its pathogenesis and their relationships to the neurophysiological paradigms of abnormal surround inhibition, maladaptive plasticity, and impaired sensorimotor integration remain unclear.
Objective
We review the use of high-resolution structural brain imaging using voxel-based morphometry (VBM) and diffusion tensor imaging (DTI) techniques for evaluating brain changes in primary torsion dystonia and their relationships to the pathophysiology of this disorder.
Methods
ncbi.nlm.nih.gov