β-blockers may reduce mortality and risk of exacerbations in patients with chronic obstructive pulmonary disease

FH Rutten, NPA Zuithoff, E Hak… - Archives of internal …, 2010 - jamanetwork.com
Background Physicians avoid the use of β-blockers in patients with chronic obstructive
pulmonary disease (COPD) and concurrent cardiovascular disease because of concerns
about adverse pulmonary effects. We assessed the long-term effect of β-blocker use on
survival and exacerbations in patients with COPD. Methods An observational cohort study
using data from the electronic medical records of 23 general practices in the Netherlands.
The data included standardized information about daily patient contacts, diagnoses, and …