PURPOSE: Metastasis remains the main cause of death in both bladder (BCa) and prostate
(PCa) cancers. The results of chemotherapy did not show any significant improvement of the
survival the past years. Cancer research has led to the identification of signaling pathways
involved and molecular targets that could change the natural history. The epithelial-
mesenchymal transition (EMT), critical during embryonic development, becomes potentially
destructive in many epithelial tumors progression where it is inappropriately activated. The …