Persistent antinociception through repeated self-injury in patients with borderline personality disorder

W Magerl, D Burkart, A Fernandez, LG Schmidt… - Pain, 2012 - Elsevier
Patients with borderline personality disorder, mostly female, exhibit severe autoaggressive
behavior, namely an intentionally performed, nonsuicidal self-injury and severe blunting of
pain perception, the mechanism of which is hitherto not understood. Because the
nociceptive system displays a high degree of plasticity, the aim of this study was to analyze
the relationship of pain perception to self-injurious behavior. Pain perception of mechanical
and chemical noxious stimuli was studied by quantitative sensory testing in 22 patients (15 …