Immunodeficiencies with autoimmune consequences
LD Notarangelo, E Gambineri, R Badolato - Advances in immunology, 2006 - Elsevier
Far from being mutually exclusive, immunodeficiency and autoimmunity may occur
simultaneously. During the last years, analysis of Autoimmune Polyendocrinopathy–
Candidiasis–Ectodermal Dystrophy (APECED) and Immunodysregulation–
Polyendocrinopathy–Enteropathy–X‐linked (IPEX), two rare monogenic forms of
immunodeficiency associated with autoimmunity, has led to the identification of Auto
Immune Regulator (AIRE) and Forkhead Box P3 (FOXP3), essential transcriptional …
simultaneously. During the last years, analysis of Autoimmune Polyendocrinopathy–
Candidiasis–Ectodermal Dystrophy (APECED) and Immunodysregulation–
Polyendocrinopathy–Enteropathy–X‐linked (IPEX), two rare monogenic forms of
immunodeficiency associated with autoimmunity, has led to the identification of Auto
Immune Regulator (AIRE) and Forkhead Box P3 (FOXP3), essential transcriptional …