[PDF][PDF] Microvessel density, VEGF expression, and tumor-associated macrophages in breast tumors: correlations with prognostic parameters.

F Bolat, F Kayaselcuk, TZ Nursal, MC Yagmurdur… - Vascular, 2006 - researchgate.net
Angiogenesis plays an important role in tumor growth, metastasis, and prognosis. Vascular
endothelial growth factor (VEGF) is a potent endothelial mitogen and acts on the angiogenic
stimulation of human neoplasias. In infiltrative ductal carcinoma (IDC), VEGF expression is
correlated with high vascularity. Tumor-associated macrophages (TAMs) contribute to tumor
proliferation, progression and angiogenesis and have a complex role in tumor biology. In
this study, the correlations between microvessel density (MVD), VEGF expression, and …